产品货号:
Z37692
中文名称:
GADD153/DDIT3抗体
英文名称:
Anti-GADD153/DDIT3 Antibody (Clone#2B1)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-GADD153/DDIT3 Antibody (Clone#2B1) |
指标别名 | CEBPZ;CHOP;CHOP 10;CHOP;GADD153;DDIT 3;DDIT3;GADD153 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | DDIT3 |
克隆号 | 2B1 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Synthetic Peptide of CHOP |
计算分子量 | 19KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | Protein A purified |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | DNA damage-inducible transcript 3,also known as C/EBP homologous protein (CHOP),is a pro-apoptotictranscription factor that is encoded by the DDIT3 gene.It is mapped to 12q13.3.This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors.The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members,such as C/EBP and LAP (liver activator protein),and preventing their DNA binding activity.The protein is implicated in adipogenesis and erythropoiesis,is activated by endoplasmic reticulum stress,and promotes apoptosis.Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma.Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. |
Uniprot ID | P35638 |
基因名全称 | DNA damage-inducible transcript 3 protein |
推荐稀释比 | WB,1:1000~2000 IHC,1:100~200 |
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